Do two intravenous iron sucrose preparations have the same efficacy?

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Do two intravenous iron sucrose preparations have the same efficacy?

BACKGROUND Intravenous (i.v.) iron sucrose similar (ISS) preparations are available but clinical comparisons with the originator iron sucrose (IS) are lacking. METHODS The impact of switching from IS to ISS on anaemia and iron parameters was assessed in a sequential observational study comparing two periods of 27 weeks each in 75 stable haemodialysis (HD) patients receiving i.v. iron weekly a...

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Safety and Efficacy of Intravenous Administration of Iron Preparations.

Iron deficiency is the main cause of anemia worldwide. Iron supplementation leads to a rise of transferrin saturation and ferritin concentration, resulting in an increased hemoglobin level and decrease of anemia symptoms. Oral iron administration is a treatment of choice in iron deficiency anemia. In patients with impaired iron absorption from the gastrointestinal tract, as well as in large def...

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Efficacy and safety of intravenous iron sucrose in treating adults with iron deficiency anemia

BACKGROUND Iron deficiency is the most common disorder in the world, affecting approximately 25% of the world`s population and the most common cause of anemia. OBJECTIVE To evaluate the efficacy and safety of intravenous iron sucrose (IS) in the treatment of adults with iron deficiency anemia METHODS Eighty-six adult patients with iron deficiency anemia, who had intolerance or showed no eff...

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Bioavailability and stability of intravenous iron sucrose originator versus generic iron sucrose AZAD.

CONTEXT Severe iron deficiency requires intravenous iron supplementation to replenish iron stores. Intravenous iron sucrose has been used for decades for the treatment of anemia. New generic iron sucrose products are now marketed for the use in several countries and there is an ongoing discussion about the safety and efficacy of iron sucrose similars. OBJECTIVE In this study, we compared the ...

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ژورنال

عنوان ژورنال: Nephrology Dialysis Transplantation

سال: 2011

ISSN: 0931-0509,1460-2385

DOI: 10.1093/ndt/gfr024